Jardiance vs Glucophage

A side-by-side look at two diabetes medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

CA JardianceCA Glucophage
Generic nameempagliflozinmetformin
Drug classSGLT2 InhibitorBiguanide
TreatsType 2 diabetes, heart failure, chronic kidney diseaseType 2 diabetes
CategoryDiabetesDiabetes
ManufacturerBoehringer Ingelheim/Eli LillyMerck/EMD (generic)
Year approved20141972
FDA warningNo boxed warningBlack box warning
Est. TV ad spend$55M$2M
Common side effectsUrinary tract infections, Yeast infections, Increased urination, Low blood pressureNausea, Diarrhea, Abdominal discomfort, Vitamin B12 deficiency

Frequently asked questions

Is Jardiance or Glucophage better?

Neither is universally "better." Jardiance (empagliflozin) and Glucophage (metformin) are both used for diabetes, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Jardiance and Glucophage?

Jardiance is a SGLT2 Inhibitor made by Boehringer Ingelheim/Eli Lilly, while Glucophage is a Biguanide made by Merck/EMD (generic). See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Jardiance has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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