Jardiance vs Trulicity

A side-by-side look at two diabetes medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US JardianceUS Trulicity
Generic nameempagliflozindulaglutide
Drug classSGLT2 InhibitorGLP-1 Receptor Agonist
TreatsType 2 diabetes, heart failure, chronic kidney diseaseType 2 diabetes
CategoryDiabetesDiabetes
ManufacturerBoehringer Ingelheim/Eli LillyEli Lilly
Year approved20142014
FDA warningNo boxed warningBlack box warning
Est. TV ad spend$280M$240M
Common side effectsUrinary tract infections, Yeast infections, Increased urination, Low blood pressureNausea, Diarrhea, Vomiting, Abdominal pain

Frequently asked questions

Is Jardiance or Trulicity better?

Neither is universally "better." Jardiance (empagliflozin) and Trulicity (dulaglutide) are both used for diabetes, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Jardiance and Trulicity?

Jardiance is a SGLT2 Inhibitor made by Boehringer Ingelheim/Eli Lilly, while Trulicity is a GLP-1 Receptor Agonist made by Eli Lilly. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Jardiance has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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