Opdivo vs Lynparza

A side-by-side look at two oncology medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US OpdivoUS Lynparza
Generic namenivolumabolaparib
Drug classPD-1 Inhibitor (Immunotherapy)PARP Inhibitor
TreatsMultiple cancersOvarian, breast, prostate, and pancreatic cancers
CategoryOncologyOncology
ManufacturerBristol-Myers SquibbAstraZeneca
Year approved20142014
FDA warningModerate warningsModerate warnings
Est. TV ad spend$150M
Common side effectsImmune-related side effects, Fatigue, Rash, DiarrheaNausea, Fatigue, Low blood counts, Risk of blood cancers (MDS/AML)

Frequently asked questions

Is Opdivo or Lynparza better?

Neither is universally "better." Opdivo (nivolumab) and Lynparza (olaparib) are both used for oncology, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Opdivo and Lynparza?

Opdivo is a PD-1 Inhibitor (Immunotherapy) made by Bristol-Myers Squibb, while Lynparza is a PARP Inhibitor made by AstraZeneca. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Opdivo has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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