Restasis vs Eylea

A side-by-side look at two eye health medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US RestasisUS Eylea
Generic namecyclosporine ophthalmic emulsionaflibercept
Drug classCalcineurin Inhibitor (Eye Drop)VEGF Inhibitor (Eye Injection)
TreatsChronic dry eyeWet macular degeneration, diabetic eye disease
CategoryEye HealthEye Health
ManufacturerAbbVie (Allergan)Regeneron
Year approved20032011
FDA warningNo boxed warningNo boxed warning
Est. TV ad spend$100M$90M
Common side effectsBurning sensation, Eye redness, Watery eyes, Blurred visionEye floaters, Eye pain, Increased eye pressure, Bleeding in the eye

Frequently asked questions

Is Restasis or Eylea better?

Neither is universally "better." Restasis (cyclosporine ophthalmic emulsion) and Eylea (aflibercept) are both used for eye health, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Restasis and Eylea?

Restasis is a Calcineurin Inhibitor (Eye Drop) made by AbbVie (Allergan), while Eylea is a VEGF Inhibitor (Eye Injection) made by Regeneron. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Restasis has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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