Restasis vs Tepezza

A side-by-side look at two eye health medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US RestasisUS Tepezza
Generic namecyclosporine ophthalmic emulsionteprotumumab
Drug classCalcineurin Inhibitor (Eye Drop)IGF-1R Inhibitor (Biologic)
TreatsChronic dry eyeThyroid eye disease
CategoryEye HealthEye Health
ManufacturerAbbVie (Allergan)Amgen
Year approved20032020
FDA warningNo boxed warningModerate warnings
Est. TV ad spend$100M
Common side effectsBurning sensation, Eye redness, Watery eyes, Blurred visionMuscle spasms, Nausea, Hair loss, Hearing problems

Frequently asked questions

Is Restasis or Tepezza better?

Neither is universally "better." Restasis (cyclosporine ophthalmic emulsion) and Tepezza (teprotumumab) are both used for eye health, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Restasis and Tepezza?

Restasis is a Calcineurin Inhibitor (Eye Drop) made by AbbVie (Allergan), while Tepezza is a IGF-1R Inhibitor (Biologic) made by Amgen. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Restasis has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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