Tepezza

Moderate Warnings

Generic: teprotumumab

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Information reviewed July 24, 2026

Rank #94 in US TV Ads
Class: IGF-1R Inhibitor (Biologic)

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What is it for?

The first FDA-approved medicine for thyroid eye disease, an autoimmune condition that causes the eyes to bulge, become inflamed, and push forward.

Primary Condition

Thyroid eye disease

How it works

An infused antibody that blocks the IGF-1 receptor, interrupting the immune signaling that drives the swelling and tissue buildup behind the eye.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Muscle spasms
  • Nausea
  • Hair loss
  • Hearing problems
  • High blood sugar

Tepezza FAQs

What is Tepezza used for?

Tepezza (teprotumumab) is a prescription medication used to treat Thyroid eye disease. The first FDA-approved medicine for thyroid eye disease, an autoimmune condition that causes the eyes to bulge, become inflamed, and push forward.

How does Tepezza work?

An infused antibody that blocks the IGF-1 receptor, interrupting the immune signaling that drives the swelling and tissue buildup behind the eye.

What are the common side effects of Tepezza?

Commonly reported side effects of Tepezza include Muscle spasms, Nausea, Hair loss, Hearing problems, and High blood sugar. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Tepezza have any serious warnings?

Tepezza has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Tepezza.

What is the generic name for Tepezza?

The active ingredient in Tepezza is teprotumumab, which belongs to a class of medicines known as IGF-1R Inhibitor (Biologic).

Who makes Tepezza?

Tepezza is manufactured by Amgen. It was first approved in 2020.

How can I save money on Tepezza?

You may be able to lower the cost of Tepezza by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Tepezza

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Quick Facts

Manufacturer

Amgen

Year Approved

2020

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