Tepezza Side Effects

Common and serious side effects of Tepezza (teprotumumab), what to watch for, and when to call your doctor.

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Information reviewed July 24, 2026

Common side effects

This is not a complete list. Always consult a doctor or pharmacist.

  • Muscle spasms
  • Nausea
  • Hair loss
  • Hearing problems
  • High blood sugar

Serious warnings

Tepezza has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Tepezza.

When to call a doctor

As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.

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Frequently asked questions

What are the most common side effects of Tepezza?

Commonly reported side effects of Tepezza (teprotumumab) include Muscle spasms, Nausea, Hair loss, Hearing problems, and High blood sugar. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Tepezza have any serious or boxed warnings?

Tepezza has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Tepezza.

When should I call my doctor about Tepezza side effects?

As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.

Where can I find the full list of Tepezza side effects?

The side effects above are commonly reported ones recorded for Tepezza (teprotumumab); they are not a complete list. For the full prescribing information and medication guide, check the official Tepezza label or ask your doctor or pharmacist.

Should I stop taking Tepezza if I have side effects?

General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.

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