Rinvoq vs Cosentyx

A side-by-side look at two autoimmune medications advertised on TV. Informational only — not medical advice.

Share

Information reviewed July 24, 2026

US RinvoqUS Cosentyx
Generic nameupadacitinibsecukinumab
Drug classJAK InhibitorIL-17A Inhibitor (Biologic)
TreatsRheumatoid arthritis, psoriatic arthritis, eczemaPlaque psoriasis, psoriatic arthritis, ankylosing spondylitis
CategoryAutoimmuneAutoimmune
ManufacturerAbbVieNovartis
Year approved20192015
FDA warningBlack box warningModerate warnings
Est. TV ad spend$175M$160M
Common side effectsSerious infections, Blood clots, Cardiovascular events, Cancer riskRespiratory infections, Inflammatory bowel disease, Fungal infections, Injection site reactions

Frequently asked questions

Is Rinvoq or Cosentyx better?

Neither is universally "better." Rinvoq (upadacitinib) and Cosentyx (secukinumab) are both used for autoimmune, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Rinvoq and Cosentyx?

Rinvoq is a JAK Inhibitor made by AbbVie, while Cosentyx is a IL-17A Inhibitor (Biologic) made by Novartis. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Rinvoq has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

TVPills is independent and not affiliated with, endorsed by, or sponsored by any drug manufacturer or brand. All trademarks are the property of their respective owners. Some links are affiliate links; we may earn a commission at no extra cost to you.