Taltz vs Stelara
A side-by-side look at two autoimmune medications advertised on TV. Informational only — not medical advice.
| US Taltz | US Stelara | |
|---|---|---|
| Generic name | ixekizumab | ustekinumab |
| Drug class | IL-17A Inhibitor (Biologic) | IL-12/IL-23 Inhibitor (Biologic) |
| Treats | Plaque psoriasis, psoriatic arthritis, ankylosing spondylitis | Psoriasis, Crohn's disease, ulcerative colitis |
| Category | Autoimmune | Autoimmune |
| Manufacturer | Eli Lilly | Janssen |
| Year approved | 2016 | 2009 |
| FDA warning | Moderate warnings | Moderate warnings |
| Est. TV ad spend | $190M | $130M |
| Common side effects | Injection site reactions, Respiratory infections, Inflammatory bowel disease, Low white blood cell count | Serious infections, Headache, Fatigue, Injection site reactions |
Frequently asked questions
Is Taltz or Stelara better?
Neither is universally "better." Taltz (ixekizumab) and Stelara (ustekinumab) are both used for autoimmune, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.
What's the difference between Taltz and Stelara?
Taltz is a IL-17A Inhibitor (Biologic) made by Eli Lilly, while Stelara is a IL-12/IL-23 Inhibitor (Biologic) made by Janssen. See the table above for a side-by-side breakdown.
Which one spends more on TV ads?
Taltz has the larger estimated TV advertising budget of the two.