Xiidra vs Restasis
A side-by-side look at two eye health medications advertised on TV. Informational only — not medical advice.
Maintained by TVPills Editorial Team · Site updated November 4, 2026 (not a product-label review)
| Attribute | US Xiidra | US Restasis |
|---|---|---|
| Generic name | lifitegrast Unverified catalogue summary (Generic name) for Xiidra in US; not checked against current local product information. | cyclosporine ophthalmic emulsion Unverified catalogue summary (Generic name) for Restasis in US; not checked against current local product information. |
| Drug class | See official local label Unverified catalogue summary (Drug class) for Xiidra in US; not checked against current local product information. | See official local label Unverified catalogue summary (Drug class) for Restasis in US; not checked against current local product information. |
| Treats | Dry eye disease Unverified catalogue summary (Treats) for Xiidra in US; not checked against current local product information. | Reduced tear production associated with ocular inflammation in keratoconjunctivitis sicca Unverified catalogue summary (Treats) for Restasis in US; not checked against current local product information. |
| Category | Eye Health Unverified catalogue summary (Category) for Xiidra in US; not checked against current local product information. | Eye Health Unverified catalogue summary (Category) for Restasis in US; not checked against current local product information. |
| Manufacturer | Bausch & Lomb Americas Inc. (US distributor) Unverified catalogue summary (Manufacturer) for Xiidra in US; not checked against current local product information. | AbbVie Inc. (US distributor) Unverified catalogue summary (Manufacturer) for Restasis in US; not checked against current local product information. |
| Year approved | — Unverified catalogue summary (Year approved) for Xiidra in US; not checked against current local product information. | — Unverified catalogue summary (Year approved) for Restasis in US; not checked against current local product information. |
| Catalogue warning level | Safety summary withheld — check official label Unverified catalogue summary (Catalogue warning level) for Xiidra in US; not checked against current local product information. | Safety summary withheld — check official label Unverified catalogue summary (Catalogue warning level) for Restasis in US; not checked against current local product information. |
| Est. TV ad spend | $150M | $100M |
| Side effects and serious risks | — Unverified catalogue summary (Side effects and serious risks) for Xiidra in US; not checked against current local product information. | — Unverified catalogue summary (Side effects and serious risks) for Restasis in US; not checked against current local product information. |
Sources and editorial standards
Use the current DailyMed labels to verify approved uses, boxed warnings, and side effects for each medication. Label results can differ by product, strength, and formulation.
Page updated November 4, 2026; the linked resources have not necessarily been reviewed on this date.
Frequently asked questions
Is Xiidra or Restasis better?
This directory does not compare clinical effectiveness or safety. Listing Xiidra and Restasis together does not establish shared approved indications, equivalence or suitability as substitutes. Consult the correct local labels and your prescriber.
What's the difference between Xiidra and Restasis?
The table shows catalogue identification and estimated advertising information for Xiidra and Restasis, not a verified medical comparison. Medical descriptions, mechanisms and safety summaries are withheld.
Which one spends more on TV ads?
Xiidra has the larger estimated TV advertising budget of the two.