Xtandi vs Calquence
A side-by-side look at two oncology medications advertised on TV. Informational only — not medical advice.
Maintained by TVPills Editorial Team · Site updated November 4, 2026 (not a product-label review)
| Attribute | US Xtandi | US Calquence |
|---|---|---|
| Generic name | enzalutamide Unverified catalogue summary (Generic name) for Xtandi in US; not checked against current local product information. | acalabrutinib Unverified catalogue summary (Generic name) for Calquence in US; not checked against current local product information. |
| Drug class | See official local label Unverified catalogue summary (Drug class) for Xtandi in US; not checked against current local product information. | See official local label Unverified catalogue summary (Drug class) for Calquence in US; not checked against current local product information. |
| Treats | Prostate cancer Unverified catalogue summary (Treats) for Xtandi in US; not checked against current local product information. | Chronic lymphocytic leukemia and mantle cell lymphoma Unverified catalogue summary (Treats) for Calquence in US; not checked against current local product information. |
| Category | Oncology Unverified catalogue summary (Category) for Xtandi in US; not checked against current local product information. | Oncology Unverified catalogue summary (Category) for Calquence in US; not checked against current local product information. |
| Manufacturer | Astellas Pharma US, Inc. Unverified catalogue summary (Manufacturer) for Xtandi in US; not checked against current local product information. | AstraZeneca Unverified catalogue summary (Manufacturer) for Calquence in US; not checked against current local product information. |
| Year approved | — Unverified catalogue summary (Year approved) for Xtandi in US; not checked against current local product information. | — Unverified catalogue summary (Year approved) for Calquence in US; not checked against current local product information. |
| Catalogue warning level | Safety summary withheld — check official label Unverified catalogue summary (Catalogue warning level) for Xtandi in US; not checked against current local product information. | Safety summary withheld — check official label Unverified catalogue summary (Catalogue warning level) for Calquence in US; not checked against current local product information. |
| Est. TV ad spend | $90M | — |
| Side effects and serious risks | — Unverified catalogue summary (Side effects and serious risks) for Xtandi in US; not checked against current local product information. | — Unverified catalogue summary (Side effects and serious risks) for Calquence in US; not checked against current local product information. |
Sources and editorial standards
Use the current DailyMed labels to verify approved uses, boxed warnings, and side effects for each medication. Label results can differ by product, strength, and formulation.
Page updated November 4, 2026; the linked resources have not necessarily been reviewed on this date.
Frequently asked questions
Is Xtandi or Calquence better?
This directory does not compare clinical effectiveness or safety. Listing Xtandi and Calquence together does not establish shared approved indications, equivalence or suitability as substitutes. Consult the correct local labels and your prescriber.
What's the difference between Xtandi and Calquence?
The table shows catalogue identification and estimated advertising information for Xtandi and Calquence, not a verified medical comparison. Medical descriptions, mechanisms and safety summaries are withheld.
Which one spends more on TV ads?
Xtandi has the larger estimated TV advertising budget of the two.