Evenity

Black Box Warning

Generic: romosozumab

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Information reviewed July 24, 2026

Rank #64 in US TV Ads
Class: Sclerostin Inhibitor (Biologic)

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What is it for?

A monthly injection that both builds new bone and slows bone loss in postmenopausal women at high fracture risk.

Primary Condition

Osteoporosis (high fracture risk)

How it works

Blocks sclerostin, a protein that limits bone formation, which increases bone building while reducing breakdown.

Common Side Effects

This is not a complete list of side effects. Always consult with a doctor.

  • Heart attack or stroke risk
  • Joint pain
  • Headache
  • Low blood calcium
  • Injection site reactions

Evenity FAQs

What is Evenity used for?

Evenity (romosozumab) is a prescription medication used to treat Osteoporosis (high fracture risk). A monthly injection that both builds new bone and slows bone loss in postmenopausal women at high fracture risk.

How does Evenity work?

Blocks sclerostin, a protein that limits bone formation, which increases bone building while reducing breakdown.

What are the common side effects of Evenity?

Commonly reported side effects of Evenity include Heart attack or stroke risk, Joint pain, Headache, Low blood calcium, and Injection site reactions. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Evenity have any serious warnings?

Yes. Evenity carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

What is the generic name for Evenity?

The active ingredient in Evenity is romosozumab, which belongs to a class of medicines known as Sclerostin Inhibitor (Biologic).

Who makes Evenity?

Evenity is manufactured by Amgen/UCB. It was first approved in 2019.

How can I save money on Evenity?

You may be able to lower the cost of Evenity by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.

Common questions about Evenity

Other Bone Health medications

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Quick Facts

Manufacturer

Amgen/UCB

Year Approved

2019

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