Myfembree

Myfembree (relugolix/estradiol/norethindrone) is a prescription medication used to treat Uterine fibroids and endometriosis. A once-daily pill for heavy menstrual bleeding from uterine fibroids and for moderate-to-severe endometriosis pain.

A GnRH antagonist combined with low-dose hormones that lowers the estrogen driving fibroid bleeding and endometriosis pain.

Commonly reported side effects of Myfembree include Bone density loss, Blood clot risk, Hot flashes, Abnormal bleeding, and Headache. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Yes. Myfembree carries an FDA Boxed Warning — the agency's most serious safety warning. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

The active ingredient in Myfembree is relugolix/estradiol/norethindrone, which belongs to a class of medicines known as GnRH Antagonist Combination.

Myfembree is manufactured by Myovant Sciences. It was first approved in 2021.

You may be able to lower the cost of Myfembree by using a free pharmacy discount card or by comparing prices across pharmacies before you fill your prescription. Savings vary by pharmacy and location.