Daliresp Side Effects

Common and serious side effects of Daliresp (roflumilast), what to watch for, and when to call your doctor.

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Information reviewed July 24, 2026

Common side effects

This is not a complete list. Always consult a doctor or pharmacist.

  • Diarrhea
  • Weight loss
  • Nausea
  • Headache
  • Mood changes including depression

Serious warnings

Daliresp has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Daliresp.

When to call a doctor

As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.

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Frequently asked questions

What are the most common side effects of Daliresp?

Commonly reported side effects of Daliresp (roflumilast) include Diarrhea, Weight loss, Nausea, Headache, and Mood changes including depression. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Daliresp have any serious or boxed warnings?

Daliresp has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Daliresp.

When should I call my doctor about Daliresp side effects?

As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.

Where can I find the full list of Daliresp side effects?

The side effects above are commonly reported ones recorded for Daliresp (roflumilast); they are not a complete list. For the full prescribing information and medication guide, check the official Daliresp label or ask your doctor or pharmacist.

Should I stop taking Daliresp if I have side effects?

General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.

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