Keytruda Side Effects
Common and serious side effects of Keytruda (pembrolizumab), what to watch for, and when to call your doctor.
Common side effects
This is not a complete list. Always consult a doctor or pharmacist.
- Immune-related side effects
- Fatigue
- Rash
- Diarrhea
- Hormone problems
- Pneumonitis
Serious warnings
Keytruda has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Keytruda.
When to call a doctor
As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.
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Frequently asked questions
What are the most common side effects of Keytruda?
Commonly reported side effects of Keytruda (pembrolizumab) include Immune-related side effects, Fatigue, Rash, Diarrhea, Hormone problems, and Pneumonitis. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.
Does Keytruda have any serious or boxed warnings?
Keytruda has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Keytruda.
When should I call my doctor about Keytruda side effects?
As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.
Where can I find the full list of Keytruda side effects?
The side effects above are commonly reported ones recorded for Keytruda (pembrolizumab); they are not a complete list. For the full prescribing information and medication guide, check the official Keytruda label or ask your doctor or pharmacist.
Should I stop taking Keytruda if I have side effects?
General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.