Eliquis vs Repatha

A side-by-side look at two cardiovascular medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US EliquisUS Repatha
Generic nameapixabanevolocumab
Drug classFactor Xa InhibitorPCSK9 Inhibitor (Biologic)
TreatsBlood clots, atrial fibrillationHigh cholesterol, cardiovascular disease
CategoryCardiovascularCardiovascular
ManufacturerBristol-Myers Squibb/PfizerAmgen
Year approved20122015
FDA warningBlack box warningNo boxed warning
Est. TV ad spend$350M$120M
Common side effectsSerious bleeding risk, Bruising easily, Prolonged bleeding from cuts, Blood in urine or stoolInjection site reactions, Allergic reactions, Back pain, Fatigue

Frequently asked questions

Is Eliquis or Repatha better?

Neither is universally "better." Eliquis (apixaban) and Repatha (evolocumab) are both used for cardiovascular, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Eliquis and Repatha?

Eliquis is a Factor Xa Inhibitor made by Bristol-Myers Squibb/Pfizer, while Repatha is a PCSK9 Inhibitor (Biologic) made by Amgen. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Eliquis has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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