Eylea vs Tepezza

A side-by-side look at two eye health medications advertised on TV. Informational only — not medical advice.

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Information reviewed July 24, 2026

US EyleaUS Tepezza
Generic nameafliberceptteprotumumab
Drug classVEGF Inhibitor (Eye Injection)IGF-1R Inhibitor (Biologic)
TreatsWet macular degeneration, diabetic eye diseaseThyroid eye disease
CategoryEye HealthEye Health
ManufacturerRegeneronAmgen
Year approved20112020
FDA warningNo boxed warningModerate warnings
Est. TV ad spend$90M
Common side effectsEye floaters, Eye pain, Increased eye pressure, Bleeding in the eyeMuscle spasms, Nausea, Hair loss, Hearing problems

Frequently asked questions

Is Eylea or Tepezza better?

Neither is universally "better." Eylea (aflibercept) and Tepezza (teprotumumab) are both used for eye health, but the right choice depends on your medical history, insurance and your doctor's guidance. This comparison is informational only.

What's the difference between Eylea and Tepezza?

Eylea is a VEGF Inhibitor (Eye Injection) made by Regeneron, while Tepezza is a IGF-1R Inhibitor (Biologic) made by Amgen. See the table above for a side-by-side breakdown.

Which one spends more on TV ads?

Eylea has the larger estimated TV advertising budget of the two.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

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