Enbrel Side Effects
Common and serious side effects of Enbrel (etanercept), what to watch for, and when to call your doctor.
FDA Boxed Warning
Enbrel carries the FDA's most serious safety warning. Review the full prescribing information and discuss the risks with your doctor.
Common side effects
This is not a complete list. Always consult a doctor or pharmacist.
- Serious infections
- Injection-site reactions
- Headache
- Increased cancer risk
- Higher risk of tuberculosis
Serious warnings
Enbrel carries an FDA Boxed Warning — the agency's most serious safety alert. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.
When to call a doctor
As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.
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Frequently asked questions
What are the most common side effects of Enbrel?
Commonly reported side effects of Enbrel (etanercept) include Serious infections, Injection-site reactions, Headache, Increased cancer risk, and Higher risk of tuberculosis. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.
Does Enbrel have any serious or boxed warnings?
Enbrel carries an FDA Boxed Warning — the agency's most serious safety alert. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.
When should I call my doctor about Enbrel side effects?
As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.
Where can I find the full list of Enbrel side effects?
The side effects above are commonly reported ones recorded for Enbrel (etanercept); they are not a complete list. For the full prescribing information and medication guide, check the official Enbrel label or ask your doctor or pharmacist.
Should I stop taking Enbrel if I have side effects?
General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.