Litfulo Side Effects

Common and serious side effects of Litfulo (ritlecitinib), what to watch for, and when to call your doctor.

Share

Information reviewed July 24, 2026

FDA Boxed Warning

Litfulo carries the FDA's most serious safety warning. Review the full prescribing information and discuss the risks with your doctor.

Common side effects

This is not a complete list. Always consult a doctor or pharmacist.

  • Serious infections
  • Blood clots
  • Increased cancer risk
  • Headache
  • Diarrhea

Serious warnings

Litfulo carries an FDA Boxed Warning — the agency's most serious safety alert. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

When to call a doctor

As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.

The “Talk to a doctor” buttons are affiliate links to our telehealth partners Sesame and Lyla Health. TVPills may earn a commission. This is not medical advice.

TVPills is an informational reference, not medical advice. Always talk to a licensed healthcare provider about your treatment.

Other Autoimmune medications

Compare Litfulo with other autoimmune drugs advertised on TV.

Frequently asked questions

What are the most common side effects of Litfulo?

Commonly reported side effects of Litfulo (ritlecitinib) include Serious infections, Blood clots, Increased cancer risk, Headache, and Diarrhea. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Litfulo have any serious or boxed warnings?

Litfulo carries an FDA Boxed Warning — the agency's most serious safety alert. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.

When should I call my doctor about Litfulo side effects?

As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.

Where can I find the full list of Litfulo side effects?

The side effects above are commonly reported ones recorded for Litfulo (ritlecitinib); they are not a complete list. For the full prescribing information and medication guide, check the official Litfulo label or ask your doctor or pharmacist.

Should I stop taking Litfulo if I have side effects?

General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.

TVPills

A reference tool to help identify prescription medications and supplements seen in television advertising. This is not medical advice. Always consult a healthcare professional.

TVPills is independent and not affiliated with, endorsed by, or sponsored by any drug manufacturer or brand. All trademarks are the property of their respective owners. Some links are affiliate links; we may earn a commission at no extra cost to you.