Nexium Side Effects
Common and serious side effects of Nexium (esomeprazole), what to watch for, and when to call your doctor.
Common side effects
This is not a complete list. Always consult a doctor or pharmacist.
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Low magnesium (long-term)
- Increased fracture risk (long-term)
Serious warnings
Nexium does not carry an FDA Boxed Warning, but every prescription medicine has risks and possible interactions. Always follow your doctor's instructions and read the medication guide that comes with it.
When to call a doctor
As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.
The “Talk to a doctor” buttons are affiliate links to our telehealth partners Sesame and Lyla Health. TVPills may earn a commission. This is not medical advice.
Other Gastrointestinal medications
Compare Nexium with other gastrointestinal drugs advertised on TV.
Frequently asked questions
What are the most common side effects of Nexium?
Commonly reported side effects of Nexium (esomeprazole) include Headache, Diarrhea, Nausea, Abdominal pain, Low magnesium (long-term), and Increased fracture risk (long-term). This is not a complete list — tell your doctor or pharmacist about any side effects you experience.
Does Nexium have any serious or boxed warnings?
Nexium does not carry an FDA Boxed Warning, but every prescription medicine has risks and possible interactions. Always follow your doctor's instructions and read the medication guide that comes with it.
When should I call my doctor about Nexium side effects?
As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.
Where can I find the full list of Nexium side effects?
The side effects above are commonly reported ones recorded for Nexium (esomeprazole); they are not a complete list. For the full prescribing information and medication guide, check the official Nexium label or ask your doctor or pharmacist.
Should I stop taking Nexium if I have side effects?
General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.