Erleada Side Effects

Common and serious side effects of Erleada (apalutamide), what to watch for, and when to call your doctor.

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Information reviewed July 24, 2026

Common side effects

This is not a complete list. Always consult a doctor or pharmacist.

  • Fatigue
  • Joint pain
  • Rash
  • High blood pressure
  • Falls and fractures

Serious warnings

Erleada has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Erleada.

When to call a doctor

As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.

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Frequently asked questions

What are the most common side effects of Erleada?

Commonly reported side effects of Erleada (apalutamide) include Fatigue, Joint pain, Rash, High blood pressure, and Falls and fractures. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.

Does Erleada have any serious or boxed warnings?

Erleada has notable warnings and precautions. Tell your doctor about your medical history and any other medicines or supplements you take before starting Erleada.

When should I call my doctor about Erleada side effects?

As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.

Where can I find the full list of Erleada side effects?

The side effects above are commonly reported ones recorded for Erleada (apalutamide); they are not a complete list. For the full prescribing information and medication guide, check the official Erleada label or ask your doctor or pharmacist.

Should I stop taking Erleada if I have side effects?

General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.

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