Trulance Side Effects
Common and serious side effects of Trulance (plecanatide), what to watch for, and when to call your doctor.
FDA Boxed Warning
Trulance carries the FDA's most serious safety warning. Review the full prescribing information and discuss the risks with your doctor.
Common side effects
This is not a complete list. Always consult a doctor or pharmacist.
- Diarrhea
- Should not be used in young children (boxed warning)
- Abdominal pain
- Bloating
Serious warnings
Trulance carries an FDA Boxed Warning — the agency's most serious safety alert. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.
When to call a doctor
As a general rule with any prescription medicine, contact your doctor about any side effect that is severe, persistent, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat.
The “Talk to a doctor” buttons are affiliate links to our telehealth partners Sesame and Lyla Health. TVPills may earn a commission. This is not medical advice.
Other Gastrointestinal medications
Compare Trulance with other gastrointestinal drugs advertised on TV.
Frequently asked questions
What are the most common side effects of Trulance?
Commonly reported side effects of Trulance (plecanatide) include Diarrhea, Should not be used in young children (boxed warning), Abdominal pain, and Bloating. This is not a complete list — tell your doctor or pharmacist about any side effects you experience.
Does Trulance have any serious or boxed warnings?
Trulance carries an FDA Boxed Warning — the agency's most serious safety alert. Read the full prescribing information and talk to your doctor about the risks before starting or changing treatment.
When should I call my doctor about Trulance side effects?
As a general rule with any prescription medicine, call your doctor about any side effect that is severe, doesn't go away, or worries you. General guidance is to seek emergency care for signs of a serious allergic reaction to any medicine — such as trouble breathing or swelling of the face, lips, tongue, or throat. For advice about your situation, talk to a licensed healthcare provider.
Where can I find the full list of Trulance side effects?
The side effects above are commonly reported ones recorded for Trulance (plecanatide); they are not a complete list. For the full prescribing information and medication guide, check the official Trulance label or ask your doctor or pharmacist.
Should I stop taking Trulance if I have side effects?
General medical guidance is not to stop a prescription medicine on your own without talking to your doctor first. Your doctor can advise whether to continue, adjust, or change your treatment. This page is informational and not medical advice.