Rexulti Alternatives
Drugs like Rexulti (brexpiprazole) — other mental health medications advertised on TV that may be alternatives. Informational only — not medical advice. Only your doctor can decide what's right for you.
Vraylar
cariprazine · AbbVie
Treats Bipolar disorder, schizophrenia, depression (add-on)
Caplyta
lumateperone · Intra-Cellular Therapies
Treats Schizophrenia, bipolar depression
Latuda
lurasidone · Sunovion (Sumitomo)
Treats Schizophrenia, bipolar depression
Auvelity
dextromethorphan/bupropion · Axsome Therapeutics
Treats Major depressive disorder
Abilify Maintena
aripiprazole · Otsuka
Treats Schizophrenia and bipolar I disorder
Nuplazid
pimavanserin · Acadia Pharmaceuticals
Treats Parkinson's disease psychosis
Frequently asked questions
What drugs are similar to Rexulti?
Drugs like Rexulti include other mental health medications advertised on TV such as Vraylar, Caplyta, Trintellix and more. They treat similar conditions but can differ in how they work, dosing, side effects and cost — your doctor can tell you which is the closest match for you.
What can I take instead of Rexulti?
Other mental health medications advertised on TV include Vraylar, Caplyta, Trintellix and others. The right alternative depends on your diagnosis, medical history and insurance — only your doctor can recommend a substitute for Rexulti. This page is informational only.
Is there a generic version of Rexulti?
Rexulti is sold as brexpiprazole. Whether a lower-cost generic is available depends on patent status — ask your pharmacist, and see the cost & savings page for ways to pay less.
Are these alternatives the same as Rexulti?
No. These are different mental health medications used for similar conditions. They can differ in active ingredient, how they work, dosing, side effects and cost. Use the side-by-side comparisons to see the differences, and never switch medications without medical advice.